If a patient weighs 60 kg and requires tobramycin at 4 mg/kg/day divided into three equal doses, how many mL should the nurse administer per dose based on a concentration of 40 mg/mL?

To determine the correct volume of tobramycin to administer per dose, we first need to calculate the total daily dose required for the patient based on their weight. The patient weighs 60 kg and requires 4 mg of tobramycin per kg of body weight per day.

The calculation for the total daily dosage is:

Total daily dosage = Weight in kg × Dosage per kg

Total daily dosage = 60 kg × 4 mg/kg = 240 mg

Since the total daily dosage needs to be divided into three equal doses, we will divide 240 mg by 3:

Dose per administration = Total daily dosage / Number of doses

Dose per administration = 240 mg / 3 = 80 mg

Next, we need to convert this dose into milliliters using the concentration provided, which is 40 mg/mL. To find the volume to administer per dose, we use the formula:

Volume (mL) = Dose (mg) / Concentration (mg/mL)

Volume (mL) = 80 mg / 40 mg/mL = 2 mL

This shows that the nurse should administer 2 mL per dose of tobramycin, making the choice of 2